vNN Web Server for ADMET Predictions

vNN Web Server for ADMET Predictions

In drug development, early assessments of pharmacokinetic and toxic properties are important stepping stones to avoid costly and unnecessary failures. Considerable progress has recently been made in the development of computer-based (in silico) models to estimate such properties. Nonetheless, such models can be further improved in terms of their ability to make predictions more rapidly, easily,...

Can We Estimate the Accuracy of ADMET Predictions ? Igor

Teaser: Is there a distinct relationship between the accuracy of prediction and molecular similarity? Can we estimate the accuracy of property prediction for new compounds? This manuscript contains 17 pages including an abstract, 1 table and 3 figures. 2 This article reviews recent developments in methods to access the accuracy of prediction and applicability domain of ADMET models and methods ...

PASPA: a web server for mRNA poly(A) site predictions in plants and algae

MOTIVATION Polyadenylation is an essential process during eukaryotic gene expression. Prediction of poly(A) sites helps to define the 3' end of genes, which is important for gene annotation and elucidating gene regulation mechanisms. However, due to limited knowledge of poly(A) signals, it is still challenging to predict poly(A) sites in plants and algae. PASPA is a web server for P: oly( A: ) ...

PONGO: a web server for multiple predictions of all-alpha transmembrane proteins

The annotation efforts of the BIOSAPIENS European Network of Excellence have generated several distributed annotation systems (DAS) with the aim of integrating Bioinformatics resources and annotating metazoan genomes (http://www.biosapiens.info). In this context, the PONGO DAS server (http://pongo.biocomp.unibo.it) provides the annotation on predictive basis for the all-alpha membrane proteins ...

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